Why is this study done?� Adenoviral keratitis(caused by adenovirus) is one of the most frequently diagnosed eye diseases. Most of these infections have symptoms like (Ocular itchiness and irritation, chemosis (conjunctival edema), photophobia, epiphora, foreign body sensation, epithelial keratitis, Adenoviral subepithelial infiltration is one of the most challenging complications to treat. Significant fibrotic remodeling of the corneal scarring with visual consequence Our purpose is to evaluate corneal transparency, recurrence, and visual acuity in patients with adenoviral subepithelial infiltration by first removing the infiltrative stroma with a smile and implanting fresh lenticule in the prepared stromal pocket. In addition, to show that this method is a safe therapeutic alternative treatment method in patients with adenoviral keratitis with intrastromal scarring. Current treatments of Adenoviral keratitis Systemic and topical antivirals Povidone-iodine irrigation (PVI), Immunoglobulin-based therapy, Anti-inflammatory therapy, and immunotherapy. Combination PVI/dexamethasone ophthalmic formulations Future treatment considerations include sialic acid analogs, cold atmospheric plasma, N-chlorotaurine, and benzalkonium chloride. Surgical Management:Transepithelial phototherapeutic keratectomy (PTK) with MMC 0.02%, Necessary in cases of significant fibrotic remodeling of the conjunctiva or sustained corneal scarring with visual consequence Treatment of Adenoviral Keratitis using SMILE MODULE Since 2015, we have been performing intrastromal fresh lenticule implantation for patients with advanced keratoconus. In this study, when we examined the pieces taken from fresh myopic lenticule implanted at the end of 3 years in patients with advanced keratoconus under the electron microscope, stem cells and telocyte cells that were effective in corneal regeneration were observed. In our hospital, intrastromal fresh lenticule implantation�1. advanced keratoconus�2. Corneal dystrophy�3.Herpetic corneal scar�4.Adenoviral corneal scar�and Hyperopia, presbyopia treatments� Patient and SurgicaL Technique Between 2020 and 2021, a 25-year-old female patient, She was dissatisfied despite long-term medical treatment in various hospitals using systemic and topical antivirals, topical corticosteroids, artificial tears, And anti-inflammatory therapy) Subepithelial and anterior stromal infiltration in the right cornea, and sustained corneal scarring with visual consequence Right eye. UDVA and CDVA :0.1 Snellen chart before the operation. Left eye cornea was transparent and UDVA,0.2,CDVA,1.0 -1.75 diopters Right;14 mm Hg,left 16 mmHg Electron micrographs from the control group reveal collagen fibers (yellow arrows) (A, B) and healthy keratocytes (asterisk) in close proximity to well-organized collagen fibers (red arrows) (C, D). In the keratoconus group, stromal cells (asterisk), which have apoptotic ultrastruc- ture, are also noted in the corneal stroma. The disrupted close proximity of stromal cells and the fibers are also seen in the keratoconus group (purple arrows) (E-H). In treatment groups 1 (I, J), 2 (K, L), and 3 (M-P) years after the operation, healthy stromal cells (asterisk), collagen fibers (yellow arrows), and close relationships are seen between the cells and the fibers (red arrows). Thin and longer extensions (navy arrows) (O, P), cell junctions (pink arrows) (M, N), and a secretome forming body (in yellow circle) (O, P) of telocyte-like stromal cells. Fresh Lenticule contains live stem cells and telocytes that produce keratocytes, collagen fibers, and an extracellular matrix that contribute to the cornea’s regeneration. All of these increase corneal transparency and visual acuity in patients with adenoviral keratitis.